[JACS] 我室郑南峰教授发表论文:From Racemic Metal Nanoparticles to Optically Pure Enanti-omers in One Pot

2017年10月25日

我室郑南峰教授在 JACS 发表论文:From Racemic Metal Nanoparticles to Optically Pure Enanti-omers in One Pot

文章链接:http://pubs.acs.org/doi/10.1021/jacs.7b10448

摘要:

A general strategy, using mixed ligands, is utilized to synthesize atomically precise, intrinsically chiral nanocluster [Ag78(DPPP)6(SR)42] (Ag78) where DPPP is the achiral 1,3-bis(diphenyphosphino)propane and SR=SPhCF3. Ag78 crystallizes as racemates in a centric space group. Using chiral diphosphines BDPP=2,4-bis(diphenylphosphino)pentane, the enantiomeric pair [Ag78(R/S-BDPP)6(SR)42] can be prepared with 100% optical purity. The chiral diphosphines gives separately rise to asymmetric surface coordination motifs composed of tetrahedral R3PAg(SR)3 moieties. The flexible nature of C–C–C angles between the two phosphorous atoms restricts the relative orientation of the tetrahedral R3PAg(SR)3 moieties, thereby resulting in the enantiomeric selection of the intrinsic chiral metal core. This proof-of-concept strategy raises the prospect of enantioselectively synthesizing optically pure, atomically precise chiral noble metal nanoclusters for specific applications.